Sentence examples for in addition to lifespan from inspiring English sources

In addition to lifespan extension, decreasing IIS in the worm produces a number of other phenotypic responses that are all dependent upon DAF-16, suggesting that may all be regulated by a common mechanism.

In addition to lifespan extension, long-lived dwarf strains exhibit superior health at advanced ages [ 2], and are less susceptible to age-related declines in memory, learning ability, and locomotion [ 3].

In addition to lifespan extension, our data also show that significant improvements in behavioral performance, cortical and hippocampal EEG activity and oscillatory patterning, and core body thermoregulation can also be achieved by delayed Mecp2 reactivation.

In his closing remarks, Rafael de Cabo emphasized the importance of studying healthy aging, i.e. healthspan, in addition to lifespan, arguing that aging is the major risk factor for all human disease and that the goal of aging research is to achieve not more years, but more healthy years.

In addition to life disparity, several other measures of lifespan dispersion have been proposed.

Consistent with this idea, it has been shown that a reduced calorie intake can reduce oxidative damage in certain species, in addition to extending lifespan.

In addition to extending lifespan, CR has been shown to prevent age-associated diseases and keep organisms in a relatively youthful and healthy state compared to ad libitum fed counterparts.

In addition to extending lifespan as shown here, RNAi knockdown of the class I HDAC hda-3 was shown to protect against polyglutamine-mediated toxicity in a C. elegans Huntington's disease, while knockdown of most other HDACs increased toxicity [ 95].

In addition to its lifespan-extending effects (Fig. 2A,B) when exposing adult nematodes to 100 n m of arsenite, we observe increased locomotor activity (Fig. 2C) and increased resistance against thermal stress (Fig. 2D) as well as against the catalytic free radical generator paraquat (Fig. 2E) (Fig. S1 for individual results), indicating increased resistance against oxidative stress.

Therefore, in addition to shortening chronological lifespan and stimulating apoptosis, the failure to efficiently arrest growth in G1 during nutrient depletion contributes to chronological age-dependent genome instability.

In addition to simply extending lifespan, there are other good reasons to understand the functions of IIS/DAF-16.