Phlorizin, in addition to inhibiting SGLT1 with an inhibition constant, Ki, of 0.2 µM [12] also inhibits hSGLT3 with a Ki of 120 µM [4].
In addition to inhibiting tumour growth via COX inhibition, it is possible that COX-2 inhibitors may also effect other target molecules.
In addition to inhibiting HIV/SIV-CCR5 interactions, CCR5 inhibition would block binding of the chemokine ligands CCL3 5 to CCR5, thereby also dampening inflammatory signaling.
In addition to inhibiting ERK substrate phosphorylation, several compounds identified inhibited cell proliferation.
Sorafenib treatment caused a rapid inhibition of various MAP kinases in addition to inhibiting AKT and receptor tyrosine kinases.
In addition to inhibiting methylprednisolone clearance, macrolides may also display anti-inflammatory effects.
In addition to inhibiting telomerase activity, BMP7 consistently induced a significant reduction in the size of telomeres.
In addition to inhibiting the growth of a variety of pathogens, curcumin has been shown to have nematocidal activity.
In addition to inhibiting cells' proliferation by blocking HER-2, these antibodies' efficacy could rely upon assembling of the patients' adaptive immune response.
In addition to inhibiting neutrophil recruitment into the lung lumen, BIIL 284 was also found to promote apoptosis of neutrophils that had transmigrated [156].
These data suggest that in addition to inhibiting the DLO pyrophosphatase, pyrophosphate blocks DLO glucosylation.
