Exact(6)
In conclusion, ExoTol specific to Ole e 1, in addition to inhibit specific immune response to this allergen, blocked the allergic response to a second unrelated allergen such as Bet v 1.
These results support the idea that N-cadherin negatively controls cell growth and survival in addition to inhibit cell differentiation and function in osteoblasts.
Furthermore, a subset of these inhibitors also blocks PI3K in addition to inhibit mTORC1 and mTORC2 [ 18].
Two recent studies demonstrated that chaetocin in addition to inhibit SUV39H1 enzymatic activity also reduced protein level of this methyltransferase.
In addition, to inhibit caspase 9 cleavage of caspase 3, XIAP can also inhibit caspase 3 directly (Deveraux et al., 1998).
Thus, in addition to inhibit YAP function by phosphorylation of YAP and promoting YAP nuclear exit, Mst1/2-Lats signaling can also inhibit YAP function by downregulating its expression level [ 41].
Similar(54)
Phlorizin, in addition to inhibiting SGLT1 with an inhibition constant, Ki, of 0.2 µM [12] also inhibits hSGLT3 with a Ki of 120 µM [4].
In addition to inhibiting HIV/SIV-CCR5 interactions, CCR5 inhibition would block binding of the chemokine ligands CCL3 5 to CCR5, thereby also dampening inflammatory signaling.
In addition to inhibiting tumour growth via COX inhibition, it is possible that COX-2 inhibitors may also effect other target molecules.
In addition to inhibiting ERK substrate phosphorylation, several compounds identified inhibited cell proliferation.
Sorafenib treatment caused a rapid inhibition of various MAP kinases in addition to inhibiting AKT and receptor tyrosine kinases.
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