In addition to Glut-4-mediated glucose uptake, stimulation of glycolysis can also be enhanced by increasing levels of fructose-2-6-phosphate through activation of 6-phosphofructo-2-kinase (PFK-2) [45] and pyruvate dehydrogenase (PDH) through activation of pyruvate dehydrogenase phosphate phosphatase (PDHP) [46].
In addition to Glut-1, several potential endogenous markers of hypoxia are currently under investigation including HIF-1 α, HIF-2 α, CAIX and VEGF.
In addition to GLUTs-1 and −4, several of the newly identified GLUT transporters, including the Class III isoforms GLUTs-8, -10, and −12, have been detected in cardiac tissue [ 10- 14].
GLUT12 is currently hypothesized to act as a second insulin-responsive GLUT in addition to GLUT4.
In addition to a glut in natural gas, Chesapeake is burdened by some $13 billion in debt.
In addition to the glut of cars and trucks, "the buses are always full," she said.
In addition to the inventory glut, Mr. Bryant attributed the margin drop to a shift in demand away from higher-margin products like microprocessors used in personal computers to less expensive products like motherboards and chipsets.
A recent study suggests that, in addition to SVCT2 and GLUTs, the water channel AQP0 may also be involved in the transport of ascorbic acid since its expression was increased in diabetic rats and upon ascorbic acid treatment [ 55].
In addition to rising air pollution, the glut of traffic means accident rates are high, with pedestrians and cyclists the most common victims.
In addition to Sorkin, it's got a glut of top-tier talent behind it, namely director Bartlett Sher, star Jeff Daniels, and producer Scott Rudin, who has enough Tony Awards at this point to forge them into his own glitzy version of the Iron Throne.
In addition to the lack of credit in Spain, a glut of finished properties has halted the sale of off-plan developments.
