The datasets for the study were obtained from three Ontario sites – Greensborough, Cookstown, and Alcona – in addition to datasets mined from the literature for three additional sites – Treynor, Iowa, Coshocton, Ohio and Cordoba, Spain.
These analyses highlight an important message: reliable calculations of co-fluctuating networks of residues from multiple sequence alignments may introduce a reproducibility/accuracy tradeoff in addition to dataset-to-dataset variability, and there may be no "one-size-fits-all" method.
In addition to the dataset derived from RefSeq, a control dataset was generated from the viral genomic sequences by conserving only open reading frames longer than or equal to 300 bp that exhibit significant sequence similarity hits to database sequences from cellular organisms or distantly related virus, using BLASTP [ 71] against SwissProt/TrEMBL [ 72] and the viral RefSeq databases.
In addition to the dataset we release a guide to the dataset structure and several csv files containing names and technical information, such as metadata tags, of all the collected media.
In addition to EGFR10 dataset, we also developed and evaluated our models on additional datasets EGFR100 and EGFR1000.
In addition to the dataset generated as described above, two additional data sets were used in the comparison of quantification methods shown in Fig. 3.
A reasonable validation process involves the use of real biological datasets, in addition to synthetic datasets which provide both ground truth and unlimited sample length.
In addition to CSAR dataset, the 'Validation' section has now been updated to include the analysis carried out on the 'PDBbind' dataset to assess the significance of ΔΔG scores reported.
In addition to these, dataset 'B' also contains files with artifacts and extra sounds and is more challenging.
We have demonstrated that discretization can often be used to generate new features which should be used in addition to the dataset's non-discretized features.
