Sentence examples for in addition to alterations from inspiring English sources

However, both of these conditions induce multiple changes in addition to alterations in EAAT2 expression that could potentially contribute to neuroprotection.

Micromechanical analyses trace this negative impact to the increase of K m over time, in addition to alterations in the fiber/matrix interface properties that reduce the J b ′ value over time.

Further, in addition to alterations in the expressions of iNOS, IKKβ, IKBα and NF-κB subunits RelA-p65/RelB-p50 RelA-p65/RelB-p50 RelA-p65/RelB-p50 cells observedrent brain regions (hypothelamus, basolateral amygdala aneuronsbrandcortex), enhanced expression of microglial cells and astrofytic GFAP was also foundifferent the treated groups compared to control.

In addition to alterations of the insulin/glucagon axis, the direct effect of chronic hyperglycemia may affect the expression level of PGC-1α.

In addition to alterations in BRCA1 and BRCA2, mutation of the p53 gene is reported in 70 90% of patients with familial breast and ovarian cancer syndrome [11], [12], [13], [14].

A key signaling molecule in the CNS involved in neurite growth [22], deletion of Ptprd leads to learning and feeding impairments, in addition to alterations in hippocampal long-term potentiation [23].

In addition to alteration of protein levels, the overall activity of the Drosha/DGCR8 complex may be altered under some circumstances.

Increased intestinal coliform colonization in addition to alteration in Lactobacillus abundance and distribution may play an important role in its pathogenesis.

Intestinal mucosa is leaky in celiac disease (CD), and this alteration may involve changes in hydrophobicity of the mucus surface barrier in addition to alteration of the epithelial barrier.

In addition to alteration of nucleosome positioning as a cell transits through mitotic division [ 8], there are a number of posttranslational histone modifications that are either maintained or changed, and which may impact gene expression after mitotic exit [ 9 12].

In addition to genetic alterations, epigenetic alterations can affect the cancer transcriptome more extensively.