Sentence examples for in addition to activation from inspiring English sources
These findings suggest that reduced PTEN levels could contribute to resistance to endocrine therapy by reducing the level of ER and its signaling activity in addition to activation of the PI3K pathway, which mediates its own intrinsic growth- and survival-promoting signals.
In addition to activation of p53, short telomeres activate the stress kinase p38 that can also induce cell cycle arrest (Iwasa et al. 2003).
In addition to activation of Smad signaling, TGF-β1 can also activate several noncanonical mitogen-activated protein kinase pathways, namely extracellular signal-related kinase (ERK), p38 MAPK, and c-Jun-N-terminal kinase (JNK) [ 37, 38].
In addition to activation of the Smad signal transduction pathway, TGF-β activates the mitogen activated protein kinase (MAPK) family [ 21].
Notably, in addition to activation of ERK1/2 and AKT, FLT3 ITD can potently activate STAT5 [ 6, 7].
FAM150A and FAM150B bind to the ECD of ALK and, in addition to activation of wild-type ALK, are able to drive 'superactivation' of activated ALK mutants from neuroblastoma.
There is accumulating evidence that, in addition to activation-induced cell death or anergy, T-cell-mediated dominant control of self-reactive T cells represents one mechanism for maintaining immunological tolerance [ 1- 3].
We found that addition of U0126 to the cell culture medium prevented ERK activation, as expected, in addition to cPLA2 activation.
In addition to TRPV1 activation in the sensory nerves, TRPV1 activation in human epidermal keratinocytes by capsaicin, acidification or ultraviolet (UV) radiation evoked an increase in the iCa2+ concentration (Inoue et al., 2002; Lee et al., 2009).
In addition to the activation signature, additional miRNAs are differently expressed in CLL compared to untransformed B cells.
Current evidence suggests that immunotherapy for cancer or infectious diseases will require the activation of CD4+ T cells in addition to the activation of cytotoxic CD8+ T cells.
