Notably, in addition to functionally interacting regulated genes, bi-fan motifs with functionally interacting transcription factors are also significant in all the growth conditions.
In addition, these functionally active compounds show high passive permeability and low susceptibility to phosphoglycoprotein mediated efflux, predictive of good CNS exposure.
In addition, a functionally graded diffusion media design is proposed that provides a better performance than conventional diffusion media at elevated temperature operation.
In addition, we functionally identified the cortical eye fields in each of our 10 subjects using functional MRI and a standard eye movement paradigm (see Materials and Methods) (Fig. 2).
In addition, Epha4a functionally interacts with Efnb2a and Efnb1 in other contexts (Cooke et al., 2005; Durbin et al., 1998; Miao and Wang, 2009), and the complementary expression of epha2 and efnb1 in some tissues has led to the suggestion that this Eph/Ephrin pair might also be functionally relevant (Miao and Wang, 2009).
Therefore, additional studies will be required to elucidate the bases of Akt-1 activation by p110α/p85β and p110α/p55γ in HIEC cells, in addition to functionally identifying their roles in the regulation of Bcl-2 homologs, thus leading to a better understanding of their distinct contributions in HIEC cell survival.
In addition to functionally interpreting single HM experiments, it is also possible to examine bivalent or trivalent HM signatures together (e.g. H3K4me3 and H3K27me3) with Broad-Enrich and compare the results with the HMs individually to determine if bivalency leads to unique biological function.
In addition, mir-202-3p functionally decreases Ppargc1a mRNA levels in AML12 cells.
In addition, two novel functionally relevant residues that result in defective APOBEC3G encapsidation, R122 and W127, cluster at the surface.
