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In addition, checkpoint signaling through ATR and CHK protein kinases is also suppressed in these cancers.
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36 In addition, immune checkpoint blockade therapy is less effective in some types of cancers.
In addition, more checkpoints have been erected, thereby preventing undocumented women from venturing too far from their communities to find care.
In addition to checkpoint-related genes, this network also recovered APN1, MAG1, and REV3, which all are involved in DNA repair [34], [35], [36].
In addition, all seven checkpoint proteins are phosphorylated, suggesting that protein phosphorylation may play a central role in controlling the checkpoint (3, 6).
He said Iraqi security forces need to beef up nighttime operations and set up more surprise checkpoints, in addition to the permanent checkpoints established throughout Baghdad.
In addition to the checkpoint defect in swi3-NBT7, E40 and E31, these cells showed strong accumulation of spontaneous Rad22 DNA repair foci, indicative of DNA damage (Figure 6B).
Thus, in addition to its checkpoint control function, hRad9 may play a role in regulating apoptosis.
In addition, the G2/M checkpoint seems to have a defined threshold of 10 to 20 DSBs [ 37, 38].
In addition, a conserved checkpoint gene, clk-2, first discovered in C. elegans seems to act in a genetic pathway parallel to the 9-1-1 complex [ 1- 4].
In addition, cell-cycle checkpoint regulation and aryl hydrocarbon receptor (AhR) signalling were deregulated at all time points, with the most significant changes seen after a 24-h exposure.
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