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KS and TM carried out operation of the patients and participated in acquisition of informed consent and study design.
SJH carried out operation of the patients and participated in acquisition of informed consent and preparing the manuscript.
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PC was also involved in acquisition of data, consent inform and Ethical Committee relationships and clinical follow-up.
FG: participated in design, statistical analyses and interpretation of data and in manuscript revision, PC was involved in acquisition of data, consent inform and Ethical Committee relationships and clinical follow-up.
Written informed consent for participation in acquisition of TCD images was obtained from the patient themselves, or parent/guardian/relative of the patient.
WHE participated in acquisition of data.
MT participated in acquisition of data.
FFein participated in acquisition of data.
TU participated in acquisition of data.
CO participated in acquisition of data.
LJAS participated in acquisition of data.
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