In contrast, a widespread decrease in thickness of the ONL was found in the retina of affected sheep, along with a reduction in the number of photoreceptor nuclei.
Our network-centrality analysis reveals a widespread decrease in connectivity in most cortical and subcortical areas.
These pathways are activated in response to noxious stimuli, leading to a widespread decrease in pain sensitivity after exposure to an acutely painful stimulus.
K. pneumoniae was one of the few organisms that showed a widespread decrease in susceptibility to all the antimicrobials tested in this study.
TBSS analysis showed a widespread decreased FA in all patients vs. controls (Fig. 1a).
Ten hertz of tACS did not result in an online effect, but in a widespread offline BOLD decrease over the occipital, temporal, and frontal areas.
An SPM analysis evidenced a striking and widespread decrease in cerebral 5-HT1A binding in ALS patients compared with controls in both motor and extramotor regions, with the most marked changes in frontotemporal regions.
Growing body of evidence showed that patients affected with schizophrenia demonstrate cognitive deficit [ 31, 32] and cholinergic abnormalities, such as reduced acetylcholine in different brain structures [ 33] as well as widespread decrease in the level of muscarinic receptors in the postmortem brain [ 34– 34].
Indeed, a number of pioneering laboratories have already successfully implemented NGS-based gene panels in a diagnostic setting, but routine application in a widespread clinical context requires a further decrease in costs and run times.
The SAT1 gene encodes the rate-limiting enzyme in polyamine catabolism, and has provided the most compelling evidence for the involvement of dysregulated polyamine catabolism in psychiatric conditions, particularly in completed suicide where it displays widespread decreases in expression across the brain [21], [22], [24], [25].
