Sentence examples for in a unique conformation from inspiring English sources

Comparison to other DHPS structures reveals that the M. tuberculosis DHPS structure is in a unique conformation in which loop 1 closes over the active site.

Furthermore, TRF2, via its highly-basic N-terminus, interacts with 4-way junction DNA [41], increasing its rate of formation and stabilizing it in a unique conformation, thereby inhibiting junction resolving activities [44].

This may be an effect of the amphipol locking the supercomplex in a unique conformation.

Amphipols may restrict large-scale movements of transmembrane helices, for example in the membrane arm of complex I, and lock the assembly in a unique conformation, which would be an advantage for single-particle cryo-EM studies.

Structural modifications of 1, which lock the aromatic backbone into a unique conformation, while maintaining the same space distribution between the nucleobases as in 1, were investigated.

A loop that is antigenic in other serotypes has a unique conformation in AAV-DJ that would conflict with the binding of an AAV-2 neutralizing monoclonal antibody.

As to the aphid control, the species-selective insecticide strategy described above can be extended to targeting a residue in aphid AChEs that adopts a unique conformation in the 3D aphid AChE structures (which we refer to as an "aphid-conformation" residue) in comparison to the same residue in AChEs of other species.

However, this hypothesis disagrees with the topology of oleosin in reticulum membrane, since oleosin adopts a unique conformation in which the H domain resides completely within the lipid bilayer and is flanked by the hydrophilic N and C domains facing the cytosol [23], [24], [25].

In the latter protein, a unique conformation of the L3,4 loop restrains the pseudo-substrate, thereby exposing the carbonyl carbon atom to nucleophilic attack.

The ΔPhe-Trp is a newly designed moiety that was found inducing a unique conformation in peptides.

These results demonstrated that amino acids in ZP6248 V3 might form a unique conformation that was critical for the interaction with GPR15 while the amino acids at position 314 in the V3 crown of ZP6248 played a key role in interaction with both CCR5 and GPR15.