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"in a time-dependent manner" is a correct and usable phrase in written English.
It can be used to describe an action or process that is influenced by time or changes over time. Here is an example sentence: "The bacteria multiplied in a time-dependent manner, with the population doubling every hour."
Exact(58)
(B) DSS1-protein adducts formed in a time-dependent manner.
The intracellular SeNPs@Am increased in a time-dependent manner.
Both viruses were inactivated in a time-dependent manner.
p62 expression was significantly decreased in a time-dependent manner.
The average ISQ increased in a time-dependent manner at each group.
Additionally, the ALP activity increased in a time-dependent manner up to 14 days of incubation.
GTN infusion in vivo induced a significant mast cell degranulation in a time-dependent manner.
As expected, these values were increased in a time-dependent manner.
B 1-octanol at 1% inhibits C. elegans feeding in a time-dependent manner.
Similar(2)
Resveratrol inhibited the phosphorylation of PI3K and AKT in a time dependent manner.
Treatment with RA significantly increased MICB mRNA expression in a time dependent manner.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com