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Partially conserved residues must only be present in a threshold of samples and the less than full conservation of an amino acid takes precedence over the conservation of a category.
The Simes procedure was also used to control the FDR when testing difference in effect between the two ethnicities, resulting in a threshold of 0.012 and 0.008 for spine and hip BMD, respectively.
For CHCO, this resulted in a threshold of 4 cases per week.
For non-seminomatous germ cell cancer patients an estimated benefit of 30% and harm of 5% resulted in a threshold of 17% (block 1).
This resulted in a threshold of 47% for D. affinis, 52% for D. lowei, 59% for D. miranda and 53% for D. persimilis.
This indicates that accepting 5% revision at 10 years resulted in a threshold of 0.15 mm for acceptable subsidence at 2 years.
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We define the persistence length of a genomic region as the maximal length in which a threshold of percent identity level, measured in a sliding window, is maintained.
In TKR, a threshold of 3 degrees of deviation in the coronal plane has been reported to increase the risk of loosening (Mason et al. 2007).
In general, a threshold of 1e-3 is usually a good choice in reality.
For example, in ATXN1, a threshold of approximately 40 glutamines is critical for disease initiation.
In the Netherlands, a threshold of €20,000 per QALY is often cited.
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