In summary, a strong decline in the number of MSCs can be observed in early adulthood as soon as skeletal growth is completed, but this reduction does not contribute to the frequently observed reduction in bone matrix density in old age (Kassem and Marie 2011).
While MSP1 showed earlier staining in microspores then a strong decline in mature flowers, MSP2 and MSP3 initiate expression in microspores, but GUS expression peaks later and accumulates in mature pollen.
Because adolescents in general experience a strong decline in HRQOL, the scores of the patient sample converge to the healthy adolescents' scores.
In both cultures, genes in pmoCAB1 operon showed a significantly higher expression levels whereas those involved in pmoCAB2 showed a strong decline in their expression as compared to μmax cell cultures (Additional file 1: Tables S5 and S10).
Analysis of LC3-II levels in control cells showed increases in the amount of LC3-II when treated with NH4Cl or E64D and PEPS A (Supplementary Figure 2a), indicative of the basal level of autophagic flux; in contrast, pyrvinium caused a strong decline in LC3-II levels in the presence or absence of lysosomal inhibitors.
We wanted to see if a strong increase in sales figures of SSRI in one year was associated with a strong decline in suicide rates in the same year; i.e. if there was a dose-response relationship.
In any case our data rule out that there is a simple linear decrease in performance with age, which contrasts with results on heat shock survival showing in various insects a strong decline during the early adult period [42], [48].
Learning: Heavy, persistent marijuana use in adolescence is linked to a strong decline in IQ.
This in turn may lead to a strong decline in anthocyanin synthesis at 20 dpa, which may be crucial for the H2O2 signaling in fiber elongation termination.
