It came to a head a year ago, when he left Boqueria in a strained split with his partner.
p.D220, a conserved R-spine residue in the F-helix that is mutated in multiple cancers (Fig. 4E), maintains the backbone conformation of the catalytic HRD motif in a "strained" conformation in the active state and loss of this conformational strain is correlated with the disassembly of the R-spine and kinase inactivation [Oruganty et al., 2013].
Huston looked astonished and, after a moment laughed in a strained way.
Unprompted, he said, in a strained voice, "Why did he do it?
At the climax, Garvey hollers in a strained key, as vocals, brass and beats fail to converge, quite magnificently.
Zimmermann, in a strained voice, said that if such regulations came to pass, "I wouldn't allow it.
"What have we ever done to you?" Tante Denise cried out in a strained, high-pitched voice.
Everybody took turns shaking his right hand, and he sounded out everybody's name in a strained, bellowing manner.
With their children grown and out of the house, husband and wife coexist in a strained marital peace.
A grand, complex human drama is reduced to platitudes and pretty pictures, as some fine actors become ciphers of suffering and resilience in a strained and superficial pageant.
"I've been a Colt for almost all of my adult life," Manning, who turns 36 this month, said in a strained voice.
