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As pathologic confirmation of all lesions (gold standard) was impossible, the results of all methods performed were subsumed in a standard of reference.
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Although FibroTest was initially proposed as a similar first-line approach to histology for prediction of 5-year survival in patients with CHC [ 37, 38], it may also serve as a standard of reference, in addition to METAVIR F staging, for evaluating the diagnostic value of ARFI LSM in baseline or chronological analysis.
Histopathological examination or clinical follow‐up including serial changes in imaging findings was used as a standard of reference.
This suggests that HR-pQCT may be used as a standard of reference for in vivo trabecular bone imaging of the distal radius and the distal tibia.
However, for the molecules to be compared, they have to be placed in a standard frame of reference.
We highlight the importance of stringent blinding protocols in order to delineate the true diagnostic accuracy of both imaging tests and discuss the difficulties of diagnostic accuracy studies in the absence of a single standard of reference, describing our approach utilising a consensus panel whilst minimising incorporation bias.
Variation in the applied standard of reference between studies is also apparent.
In order to enable comparisons between different countries in a comparable way, a standard set of reference values for all countries was used.
If the pathological TNM (pTNM) was not available as standard of reference in a patient, e.g., because that patient underwent primary radiochemotherapy, clinical TNM (cTNM) was employed.
These maps provide information about the location and variability of cortical regions in a standard reference space (the MNI space).
The development of magnetic resonance (MR) imaging has allowed it to become the standard of reference in the work-up of bone and soft tissue abnormalities of the hip.
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