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These ideas will be tied together in a speculative model that integrates peripheral and central CGRP actions in photophobia.
This is summarized in a speculative model.
These results suggest a previously unrecognized step in which HAC1 mRNA participates in Ire1 activation to promote its own cleavage and ascertain high specificity and are summarized in a speculative model in Figure 6 10.7554/eLiFigure31.013 Figure 6.
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Previously we said in discussing a speculative model for polycomb activity that, PRC2 might favour 'the increasingly compacted chromatin state created by PRC1 occupancy'.
In Fig. 8 we propose a speculative model in which ACh acts as a dispersal factor through two separate pathways.
In total, our data suggest a speculative model by which severe nutrient deprivation significantly reduces TORC1 activity in wild-type cells, resulting in decreased chromatin binding by multiple HMG proteins simultaneously.
It is of course fine to provide such a speculative model in the Discussion section of the paper.
In light of these data, we propose a speculative model for the function of PTB in the FCV life cycle detailed in figure 12.
We will finally develop a speculative model expanding in two directions on our recent proposal that fluorescent SM analogs could reveal preexisting domains stabilized by high SM concentrations, based on the capacity of BODIPY-SM domains to form excimers, indicating ordering, and on the dependence on the endogenous Lo-SM for BODIPY-SM assembly and lateral diffusion properties [31].
In any case, our current results suggest a speculative model for how coatomer is recruited onto membrane to participate in COPI vesicle formation (Fig. 6).
The potential wider conservation of the nucleoprotein fold identified in the Arteriviridae and Coronaviridae families and a speculative model for the evolution of corona-like virus architecture are discussed.
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