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An emerging approach involves the combination of multiple adjuvants in a single formulation to achieve optimal vaccine efficacy.
Ipratropium and albuterol, combined in a single formulation, is widely used as three to four times daily maintenance therapy in COPD.
The combination of this targeting strategy together with drug encapsulation in a single formulation may contribute to enhance the efficacy of these associated agents, reducing their toxicities.
A passivation approach is proposed for the guidance and control of under-actuated marine craft, which integrates trajectory planning and dynamic tasking in a single formulation.
These drugs can be given as single drug preparations or fixed dose combinations (FDCs) of two more drugs in a single formulation.
In addition, the use of polymer-modified binders (PMBs), at a content of about 4 4.5%, combined with such an optimized aggregate packing leads to the design of HiMA, which are characterized by great compactability, very high stiffness modulus, and high fatigue resistance in a single formulation, allowing for reduced pavement thickness and increased longevity.
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The simulation approach consolidates existing NMR numerical methods used in biology and engineering into a single formulation that expands on the magnetic-dipole equivalent of spin packets.
In contrast to constant-density incompressible flows, where the characteristics-based variables reconstruction leads to a single formulation, in the case of variable density flows three different schemes can be obtained henceforth labeled as: transport, conservative and hybrid schemes.
In 2012, a volume of 2 mL was described as sufficient for efficacy according to ASTM E 1174-94 formulationsions containing 62% ethanol [ 8]; also in 2012, efficacy data for a single formulation based on 70% ethanol were presented for volumes as low as 1.1 mL [ 11].
During the pivotal trial, subjects were randomized to receive a single formulation of Juvéderm in one NLF and Zyplast collagen in the opposite NLF.
In addition, this new method permits a single formulation to be obtained from the MDFpPC schemes independently of the parity of the number of steps, which facilitates the design of a computational algorithm thus permitting improved implementation in a computer.
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