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In a series of phase I clinical trials in the UK, MVA85A had an excellent safety profile and was highly immunogenic.
MVA85A was subsequently evaluated in a series of phase I trials in The Gambia, a tuberculosis-endemic area in west Africa.
These encouraging data led to the assessment of FP9-MVA ME-TRAP in a series of phase I/II studies in adults and in children in Gambia [9] and in Kenya, where lower T cell immunogenicity has been observed [10].
10, 11 These risk criteria have now been utilized in a series of Phase III clinical trials.
The recently approved TSEC pairing conjugated estrogens (CEs) with bazedoxifene (BZA) was evaluated in a series of phase 3 clinical trials in postmenopausal women [ 9- 20].
Initially in Scandinavia the approach of a hypo-fractionated 1-week course of radiotherapy performed prior to radical surgery was evaluated in a series of phase III trials.
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Kuhn's central claim is that a careful study of the history of science reveals that development in any scientific field happens via a series of phases.
In addition, a series of phase transitions such as boehmite → γ-alumina → α-alumina were observed from 500°C to 1,200°C.
It's gone in a series of phases because it was tied to the No. 7 subway.
Campbell et al. propose that the development and evaluation of such complex interventions be considered in a series of phases, analogous to the sequential phases of drug development [ 15].
Mapatumumab was evaluated first as a single agent and subsequently in combination with chemotherapeutic agents in a series of Phases 1, 1b and 2 clinical trials (Tolcher et al, 2007; Greco et al, 2008; Hotte et al, 2008; Mom et al, 2009; Trarbach et al, 2010).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com