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The animals were sacrificed with CO2 in a sedation box.
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Surgery was performed under general anesthesia by weight-adopted intraperitoneal injection of Xylazin 2 % (Medistar®; 12 mg/kg body weight) and Ketamaninhydrochlorid (Ketavet; 100 mg/ml; 80 mg/kg body weight) after sedation of the animals with isoflurane in a sedation-box.
GE Healthcare has developed a device for monitoring consciousness levels in sedated patients TW is collaborating with GE Healthcare in developing a sedation monitoring device.
In particular, a sedation protocol is essential.
Nineteen intensive care unit patients received a propofol infusion in accordance with a sedation protocol.
With limited clinical benefit of IS-trials in NICU patients, a sedation algorithm guided by commonly used sedation scales may be sufficient.
In 2009, we introduced a sedation vacation and nurse-driven, RASS-targeted sedation protocol.
An increasing number of ICUs in the UK utilize a sedation guideline and a sedation scoring tool.
The majority of responding ICUs (88%) in our survey use a sedation scoring system.
A high perentage of patients (>80 %) in both groups underwent a sedation hold during the intervention period, and 34/74 patients (46 %) were extubated.
Whereas only 8% of hospitals used a sedation scale in the first survey, this number rose to 51% in the present survey.
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