Similar(60)
However, it remains an open issue that some fetal cells may display the HSC potential even in a stringent repopulation assay but do not function as dHSCs in situ.
Depletion of Tregs by diftitox in RCC patients resulted in a refractory repopulation of 75% of the original number within 2 months in another study (Dannull et al, 2005).
Moreover, these human fetal liver multipotent progenitor cells showed features of mesenchymal-epithelial transition; retained multipotent capability to differentiate into fat, cartilage, bone, and endothelial cells; and were reported to have a repopulation capacity in a mouse model of liver injury.
At the same time, however, we found a reduction in MaSc-enriched compartment and a reduction in repopulation efficiency of RARα1/KO mammaryfragments.
To test whether the Wnt pathway was activated in irradiated tumor cells and its role in tumor repopulation, a 8×TopFlash luciferase reporter containing the wild-type LEF/TCF-binding site and a 8×FopFlash luciferase reporter containing a mutated LEF/TCF-binding site were stably transduced in Panc1 and HT29 cells.
On the other hand, cell transfer to LC2 from day-7 LC1, i.e. following a one-log reduction of cell number in LC1 and the relative enrichment of BCR/Ablprotein-negative cells (see Figures 1A and 3) [3], [3], resulted in a delayed LC2 repopulation, which reached its peak at day 21 (Figure 4B).
Rizvi and colleagues provided evidence that murine BMDCs restore murine intestinal tissue in a long term repopulation fashion suggesting that BMDCs have fused with intestinal stem and/or progenitor cells [ 29].
Indeed, there was a similar reduction in repopulation activity in Th −/− and Gata3 −/− AGMs (compare Figure 4C with Table 1 and Figure S1 with Figure S2C).
This increase in repopulation potential in in-vitro-treated AGMs was also reflected in the donor chimerism of individual (repopulated) mice (compare Figure S3 with Figure S1).
In this study, we describe an approach to in vivo cellular repopulation of a tissue-derived tubular elastin scaffold.
This provides a potential mechanism for signaling whereby extracellular events drive a shift in the repopulation of the underlying TM helix dimer energy landscape.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com