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Here we describe the design, synthesis and structure activity relationships of a series of benzimidazole-based compounds with activity against Mycobacterium tuberculosis (Mtb) in a replicating state, a physiologically-induced non-replicating state, or both.
As power is a function of both the strength of the association (effect size) and the MAF of the associated variant, limitations in transethnic replicability of variants resulting from limited allelic polymorphisms in a replicating population is a notable challenge.
Author's response: We have endeavoured to clear up some of these issues by stating that we mean all nucleotides that are to be found in a replicating system.
The origin of cellular life where genes, membranes and catalysts are integrated in a replicating whole is probably the most difficult problem in cell evolution.
The architecture of colonic crypts provides a unique model in which to investigate some of the functional consequences of age related RC deficiency in a replicating tissue.
Subgenomic fragments of morbillivirus nucleic acid that are not capable of being incorporated in a replicating morbillivirus or morbillivirus-like virus are not considered as rinderpest virus containing material (8 ).
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Twelve cows (48 DIM) were assigned to six treatments in a replicated 6 × 6 Latin square.
Twenty-four lactating Holstein cows were used in a replicated 6 × 6 Latin square design.
Eighteen Holstein cows averaging 134 ± 14 d in milk were used in a replicated 6 × 6 Latin square design with 21-d periods.
Six primiparous mid-lactation Holstein cows with ruminal cannulas were randomly assigned to 4 treatment sequences in a replicated incomplete 4 × 4 Latin square design experiment.
Eight mature idle gelding horses (mean body weight [BW], 558 ± 45 kg) were used in a replicated 2 × 2 Latin square design study.
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CEO of Professional Science Editing for Scientists @ prosciediting.com