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A not-for-dividend organisation with no shareholders, NR effectively moved into the public sector in a reclassification of its status last September when its net debt of more than £30bn came on to the government's books.
Major achievements in the understanding of thrombotic microangiopathies (TMA) have not only resulted in a reclassification of TMA but most of all they have culminated in the design of new treatments and have enabled clinicians to better delineate their prognosis.
However, in one Indian State, Andhra Pradesh, the collected data contradicted the expert classification resulting in a reclassification of the six selected Districts.
The central reading of the X-rays (central assessment) in a subset of patients (n=282 (87%)) resulted in a reclassification of some patients.
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Recently, a DHFR from the moderate thermophile Geobacillus stearothermophilus (originally named Bacillus stearothermophilus in 1920 but transferred to the genus Geobacillus following a reclassification in 2001) has been characterized and examined with respect to its structural and kinetic adaptation to moderately high temperatures.
In the event of a reclassification, they could re-contact their healthcare providers to discuss further options.
For example, a recent prospective study in T2D (Meigs et al., 2008) found that using 18 loci known to be associated with T2D in a logistic regression classifier together with known phenotypic risk factors does not significantly improve the risk classification, and leads to a reclassification in only 4% of the patients.
Neither the simple gene count score (net reclassification improvement 0.2%, −5.1 to 4.7) (table 5) nor the genetic risk function (net reclassification improvement −3.2%, −9.9 to 3.5) (web table M) resulted in a net reclassification improvement when added to the Framingham offspring risk score.
Adding TGFBR1 to the prediction of TnT resulted in a net reclassification index of 8.2%.
A threshold of 2% and 1% for low probability resulted in a net reclassification improvement of 26%16%to36o 36% and 100% (4% to 27%), respectively.
In a recent reclassification of the radiology of PMG, Barkovich [ 1] called for detailed description of the pathology of PMG and we attempt to address this.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com