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Briefly, the immunofluorescence quantification was performed using the formula: where L and R denote proximal and distal positions respectively in a parallel division and as left and right cell respectively in perpendicular division, to get the normalized ratio for PH3 and β-Catenin.
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Blocking of Shh signalling led to a sharp decrease in the number of perpendicular divisions and a corresponding increase in parallel divisions.
Previous findings have shown that adherens junctions are required to maintain the spindle in a parallel orientation during symmetrical divisions in Drosophila and mammalian epithelial cells (den Elzen et al., 2009; Lu et al., 2001).
The increase in parallel divisions at later ages observed in the current study correlates with the period of decrease in GNP proliferation during later development.
Interestingly, in Cyclopamine treated animals, there was a dramatic increase in the percentage of parallel divisions (71%), when compared to control (56%).
(In a parallel deal, an investor group led by Sony paid $2.2 billion for EMI's music publishing division).
Orthogonal frequency division multiplexing (OFDM) [1 3] is a technique used to send information over several orthogonal carriers in a parallel manner.
Grafton in a parallel universe.
They're worn in a parallel universe.
Elizabeth Hastings is Jane Eyre in a parallel universe.
Well, in a parallel universe anyway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com