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Prepulse inhibition (PPI) of the startle reflex is disrupted in a number of developmental neuropsychiatric disorders, including Tourette syndrome (TS).
Emerging literature suggests that epigenetic contributions from histone variants play key roles in a number of developmental processes such as the initiation and maintenance of pericentric heterochromatin, X-inactivation, and germ cell differentiation.
"Zika virus infection of the fetus disturbs this migration, resulting in a number of developmental abnormalities of the brain, such as microcephaly," Roos said by email.
They are involved in a number of developmental processes and are expressed in a cell-specific way [134].
Wnt proteins are secreted proteins involved in a number of developmental processes including neural development and synaptogenesis.
Previously, Capulet (Capt), the Drosophila CAP orthologue, has been shown to be involved in a number of developmental processes including oocyte polarity [18], cell morphogenesis [19], bristle morphogenesis [20], compound eye development [20] and wing disc dorsal/ventral pattern formation [19].
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Ethylene plays a role in the regulation of a number of developmental processes, often in interaction with other plant hormone signals.
In addition, Oct4/Nanog/Sox2 repress the expression of a number of developmental genes in order to maintain the undifferentiated state of ESCs.
It is interesting that the DAVID analysis of the HSF binding sites in Drosophila showed enrichment for a number of developmental processes as well as gamete formation including oogenesis (Figure 8).
The size and abundance of plastoglobules in chloroplasts are affected by a number of developmental and environmental conditions, and includes stresses (especially oxidative) and transitions from chloroplasts to gerontoplasts (i.e. senescence) and chloroplast to chromoplast transitions (e.g. as occurs in flowers and fruit).
Hedgehog (HH) signaling, and particularly signaling by sonic hedgehog (SHH), is implicated in several essential activities during morphogenesis, and its misexpression causes a number of developmental disorders in humans.
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