Exact(2)
Besides setting the resting membrane potential and determining repolarization of action potential, our previous studies showed that enhancement of I K is associated with the apoptosis, migration and maturation of neurons, depending on whether the neuron is in a normal development state or under abnormal apoptosis stimulation (Zhuang et al., 2012).
It seems to be established that there is, in general, almost a predestined mosaic pattern for development which, if carried out in a normal environment, will result in a normal development peculiar for the species.
Similar(58)
Aberdeenshire council then included that proposal as a normal development in the belief it was covered by the 2008 planning approval.
Physical activity and motor skills acquisition are of high importance for health-related prevention and a normal development in childhood.
The results showed that genetic depletion of p53 results in a completely normal development and survival of G2 tert−/− embryos (Fig. 6D).
Treatments performed at later times resulted in an almost normal development of Mc with only mild proximal defects (data not shown).
In contrast, a normal autonomy development, psychosocial development and social development was found in 32 adult Dutch PKU patients [ 22].
Overall, our data highlight that whereas EZH2 and BMI1 may function in a 'linear' pathway in normal development, their overexpression has different functional consequences for breast tumourigenesis.
Although PRC2 and PRC1 polycomb genes function in a 'linear fashion' in normal development, it has been suggested that their overexpression may have different functional consequences for breast tumorigenesis [ 9].
Prolactin plays a central role in breast development, differentiation, and lactation (reviewed in [ 1]), but experimental data suggest that, in addition to having a role in normal development, prolactin may have procarcinogenic effects (reviewed in [ 2, 3]).
In addition to a role in normal development, deregulation has been shown to be integral to cancer development and progression by, among other functions, promoting cancer cell proliferation and migration (Giles et al, 2003).
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