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On the other hand, the thickening of the epithelium associated with dysplastic progression may attenuate the excitation laser power and also obscure the collagen Raman emission from the deep collagen basal membrane (Badizadegan et al, 2004), thus resulting in a much decrease of Raman signals (875 cm−1) from dysplasia tissue.
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In contrast, heat treatment at 60 °C resulted in a much larger decrease in the same ratio and was accompanied by a blue-shift of the main PBS emission band at around 655 nm (F655), indicating an energetic decoupling of PBS from chlorophylls and reorganizations in its internal structure.
Although we observed a decrease in the brood size of wild type animals using our heat shock conditions we also observed that expression of activated hsRHO-1(G14V) in L4 stage animals resulted in a much larger decrease in brood size when compared to controls (Figure 5).
However, in these previous studies, enzymes were added directly to the cell culture medium, resulting in a much faster decrease of oxygen concentrations than in the model described here.
Furthermore, compared with NT2 cells transfected with the miR-383 mimic, cotransfection of si-IRF1 and the miR-383 mimic into cells resulted in a much more decreased cell proliferation, a more increased G1-phase population and a higher apoptotic rate.
Differences among people in their feelings about risk (and, for that matter, in how much decrease in the marginal utility of money they experience) might be accommodated by allowing utility functions individually tailored to particular personalities.
However, culturing cells in the absence of exogenous IL-2 for just 48 h resulted in a much more dramatic decrease of Bcl-2 expression in iTregs compared with activated Tconv, which was accompanied with a larger increase of Bim expression.
As shown in Figure 2E, a much larger decrease in the mean number of 5-HT-immunoreactive neurons in the dorsal raphe nucleus was produced in mice exposed to the FST compared with normal mice.
Although the expression of RXRG and THRB was moderately reduced rather than absent in group 1, a much greater decrease (six- to eight-fold) in the expression of OPN1MW/LW genes relative to group 2 suggests that group 1 retinoblastomas do not complete the cone differentiation programme and may be arrested at an earlier stage of development.
After the rapid increase in fluorescence, probably representing formation of DCC-SSB·dT70 and with a rate constant similar to that when DNA was in excess, there is a much slower decrease in fluorescence (3.4 μM−1 s−1), consistent with formation of DCC-SSB 2·dT70 DCC-SSB 2·dT70
Women also exhibited decreases in SBP and DBP with RE, but had a much greater decrease in DBP compared with men: -10 versus -2 mmHg.
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Justyna Jupowicz-Kozak
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