Sentence examples for in a mechanism of from inspiring English sources

In a mechanism of action study, compound 7a was confirmed as a 20S proteasome inhibitor in both in vitro and cell-based assays.

Finally, TTP was observed in crystals of TMPKMtub, locked by Arg14, thus providing a structural explanation for the observed inhibitory effect of TTP putatively involved in a mechanism of feedback regulation of the enzymatic activity.

Lymphatics and their role in a mechanism of sensitization have also been implicated in sympathetic ophthalmia [32].

In response to glutamine deprivation, the expression of glutamine synthetase in luminal cells allow them to produce and export glutamine to the extracellular space to support the survival of glutamine addicted basal cells in a mechanism of metabolic symbiosis.

RNA viruses show a high degree of genetic variability and the pool of variants results in a mechanism of virus evolution and survival [26].

This case was observed in a mechanism of action study of L-BLP25 in multiple myeloma.

In addition, a mechanism of temporary reprojection was used with observations for which depth information was missing.

It seems reasonable that in HuH28 a mechanism of resistance that overcomes mTOR inhibition may be active.

In animal studies, a mechanism of action for repaglinide has been postulated.

In order to determine a mechanism of action in CF models, we investigated if the selected inhibitors of the PI3K/Akt/mTOR pathway could restore defective autophagy in CF cells.

Selective alteration in high affinity agonist binding: a mechanism of beta-adrenergic receptor desensitization.