The system was capable of supporting self-care and adherence to regimen, monitoring adherence, and supporting clinician engagement with patients, as well as testing its feasibility in a long-term implementation.
Although from a public health perspective the role of schools for health promotion is very important, high demand in time and resources may impede long term implementation of intervention programs.
It was modelled and refined in analogue studies and exploratory trials in the 1960s (e.g., [ 13]); with definitive randomised controlled trials being conducted in the 1970s (e.g., [ 14]) and long term implementation studies conducted over the last twenty years [ 15, 16].
This voluntary organization advocates the cross-sectoral management of water resources and infrastructures in a long-term planning, implementation, and monitoring process, in which the boundaries of political decision making would become more aligned with natural watersheds or technological networks such a sewer systems and hydropower schemes.
However, an adapted modus operandi for a reliable assessment of this evolving technology is needed, to enable their long-term implementation in a radiation environment.
This study constitutes Part IV (long-term implementation) of a large scale complex intervention project [ 30] on the routine use of quality of life data in oncological practice.
For these complex interventions, exploratory trials (in this case, the Leuven studies) should be followed by an adequately controlled and powered study to assess replicability and finally by long-term implementation studies, testing effectiveness in uncontrolled settings [ 7].
The MRC has identified five essential steps in the evaluation of such an intervention – theory, modelling, exploratory trial, definitive randomised trial and long-term implementation [ 48].
Cost-effectiveness analysis is warranted for long-term implementation of HAI surveillance in ICUs.
