Antibodies developed with a lesser frequency in liraglutide-treated subjects than in those treated by exenatide, likely because of its greater structural similarity with human GLP-1 (97vs.52%2%).
However, under culture conditions where the DCs are compromised in their ability to secrete IL-6 in response to B7-DC XAb treatment, addition of exogenous IL-6 resulted in generation of IL-17 cells, albeit at a lesser frequency.
This apparent paradox could be explained by the low numbers of patients on cyclophosphamide, which is usually given in our unit as low-dose pulses, with a lesser frequency of infectious complications [ 17].
The fact that methylation can coexist with APC mutations in sporadic CRC has been reported by others, albeit with a lesser frequency (Gayet et al, 2001; Hawkins et al, 2002).
Other AEs, including myalgias and flushing, were reported at a lesser frequency than headache and were typically mild-to-moderate in intensity.
Antibody sub-types were predominantly "adw" (69-2%) with a lesser frequency of "ayw" (23%), while 7-87-8%re indeterminate.
A higher than usual incidence of disease is seen in Northern Europe (Scandinavia in particular), with lesser frequency in Southern Europe, making genetic predisposition in certain populations likely [1].
LOH has also been detected in much lesser frequency in ductal hyperplasia usual type, in normal breast [ 12] and in gynecomastia [ 13].
"And second, they're doing it in lesser frequency".
In the domain model, some system features included in the overall model of ideational semantics are not found, and others appear with a greater or lesser frequency.
