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The phrase "in a large scale" is correct and usable in written English.
You can use it to express that something is occurring on a large scale or at a large level. For example, "The company has undergone restructuring in a large scale in the recent years."
Exact(27)
Handheld computers for rural healthcare, experiences in a large scale implementation.
Mr. Ming does almost everything in a large scale, and some of his albums span entire walls when opened.
This year, it really happened in a large scale with multiple major mergers.
The smart grid infrastructure is being developed in a large scale.
Chemical polymerization is a conventional method to produce high quality PANI in a large scale.
However, it is difficult to synthesize nanofluids in a large scale.
Similar(33)
"We do not exclude that these tools may be used in a large-scale way".
(Yesterday the Office of Emergency Management participated in a large-scale terrorism drill at Shea Stadium).
Seashore-Ludlow, B. et al. Harnessing connectivity in a large-scale small-molecule sensitivity dataset.
Feedforward and feedback frequency-dependent interactions in a large-scale laminar network of the primate cortex.
The Stoa of Attalus was the first element in a large-scale reconstruction of the Agora.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com