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"in a large number" is correct and commonly used in written English.
You can use it to refer to a large quantity of something, for example: "This year, a large number of students applied to attend the university."
Exact(59)
I think that is indelibly set in a large number of our minds.
The report further alleges "widespread" racism in a large number of British prisons.
The OLTRS programme validates religion-orientated degrees in a large number of mostly Christian settings.
Since my release I have lived and worked in a large number of countries.
Hints, and more than hints, of homosexuality appear in a large number of his paintings.
In addition though, Britain also took in a large number of immigrants with lower numerical skills.
In a large number of cases, key beds originated as volcanic ash.
This last point will affect us in a large number of ways.
In addition, factor VIII is synthesized in a large number of other tissues.
Then in a large number of trials all outcomes should occur with approximately the same frequency.
Slavery existed in a large number of past societies whose general characteristics are well known.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com