It might be expected that the prevalence of candidal infection should be higher in those with a greater severity of illness.
Increased use of hospital services by the more disadvantaged in our population reflect their greater health need and, in many cases, also a greater severity of illness [ 23, 29].
This is presumably because patients in these settings had a greater severity of illness and are likely to have more multiple co-existing conditions than patients in other parts of the hospital.
Thus, it is likely that the increased levels of pro-inflammatory cytokines are, at least in part, due to persistent epithelial damage because of impaired anti-inflammatory M2 macrophage skewing in chemerin-treated mice, as a greater severity of epithelial damage was observed in chemerin-treated mice following DSS exposure.
The smaller changes from baseline in back pain VAS and EQ-VAS in the prior bisphosphonate users may reflect a greater severity of osteoporosis in this group of patients, as shown by their baseline clinical risk factors.
In the present study, the lesion score and body weight data alone suggest that Line A and B responses were similar in response to E. maxima-infection, whereas there was a greater severity of infection in Line A birds in response to E. acervulina and in Line B birds in response to E. tenella.
MacBeth and Gumley have shown in their review of premorbid adjustment and early symptom development that premorbid problems in psychosocial functioning are associated with a greater severity of illness course and, in particular, more negative symptoms [ 17].
However, patients who were uninsured on some visits were reported to have higher primary care, emergency department, and inpatient costs than patients in any other insurance category, suggesting a greater severity of illness among these patients.
We hypothesized that the difference in albuminuria between the two IR groups could be attributable to a greater severity of insulin resistance in the DAA−/IR group.
