Sentence examples for in a focal model from inspiring English sources

We tested the ability of EF- and FPN-hNSCs to engraft and differentiate following transplantation in a focal model of demyelination induced with a single injection of lysolecithin in the corpus callosum of adult mice.

Neuroprotection by ghrelin was demonstrated by Liu et al [ 34] in this 4-vessel occlusion model (see Table 1), and by Chung et al [ 35] in a focal ischemia model.

The first evidence for a neuroprotective effect of EPO by a peripheral route of administration was provided by Brines et al. (2000), who demonstrated in a focal stroke model a significant reduction in infarct volume by an intraperitoneally applied high dose of EPO (5000 IU/kg) up to 6 hours after reperfusion.

The present study was designed to determine the ability of melatonin to influence MMP-9 activity and BBB disruption, in a focal ischemia rat model induced by photothrombosis.

We challenged C4/−, Prnp−/− and Prnp+/+ mice in a focal cerebral ischemia model.

These findings suggest that PMC-12 may be a good candidate for recovery of damaged learning and memory function in a focal cerebral ischemia model.

These results suggest that treatment with PMC-12 may induce beneficial effects for improvement of memory function in a focal cerebral ischemia model.

We explored the noninvasive intranasal brain delivery method and investigated therapeutic effects of apelin-13 in a focal ischemic stroke model of mice.

Specifically, the present study investigates glucose transporter-1 (GLUT1) function and expression at the BBB in a focal brain ischemia model of mice pre-exposed to nicotine.

Koh identified that the MAPK/extracellular signal-regulated kinase (ERK 1/2 signaling pathway is a critical mediator of neuronal cell survival against apoptosis in a focal cerebral ischemia model in rats [ 11].

In contrast to our previous report that treatment with edaravone decreased neurogenesis in the ischemic ipsilateral subventricular zone (SVZ) in a focal cerebral ischemia model (Zhang et al., 2012), the discrepancy can be attributed to the different response of NSPCs in the DG and SVZ to cerebral ischemia/hypoxia.