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Analysis of AMPKγ deficient mice evidenced impaired PGC-1 deacetylation in correlation with a failure to adapt muscle metabolism in response to fasting or exercise [ 15, 16].
Seasonal changes in depressive symptoms are considered to be the result of a failure to adapt to the shift in day length that accompanies seasonal change [ 19].
To anyone who has stepped inside a Chuck E. Cheese in the past ten years, there's no doubt that a failure to adapt is at least partially responsible for its problems.
Cohen and Gooch ascribe the disaster at Gallipoli to a failure to adapt — a failure to take into account how reality did not conform to their expectations.
The union movement is a busted flush, ground down by technological changes and restrictive legislation, and is characterised by a failure to adapt to 21st century realities.
The level of activity dropped after the first 5-min interval in the WT mice, whereas it remained high during the entire 10 min session in Tc1 mice, indicating a failure to adapt to their environment.
Mr. Mrabet said other problems included an excessive focus in graduate training on quantity over quality; a failure to adapt courses to workplace opportunities; overcrowded lecture halls; student strikes; and school financing issues.
"One reason I left the firm was a failure to adapt," a former banker in the New York branch said.
The attenuation of H37Ra involves a failure to adapt to both changes in the environment and metabolic constraints, evidenced by the lower expression of genes involved in mycobactin synthesis and fatty acid metabolism when the attenuated strain is moved from broth culture to the macrophage.
There is a failure to adapt and thus a failure to genuinely participate in the contemporary practices the show ostensibly means to address.
Cisco faces additional pressure because of evolving markets and a failure to adapt.
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