In addition, a dramatic widening of the TMDs into the extracellular space occurs, which is very clearly observed when the fully opened outward transition state is adopted.
There has been a significant increase in volatility accompanied by a dramatic widening of credit spreads (see "Panic Spells Opportunity") and a collapse in the dot-com world.
During the same period that lawyers have suffered a decline in employment prospects, there has also been a dramatic widening of the justice gap -- the gap of legal needs that go unmet.
In her dissertation, "Brides, Billionaires and Buildings: The Gendering of Real Estate in Postsocialist China," Leta Hong Fincher, a doctoral candidate at Tsinghua University, explores what she says is "a dramatic widening of China's gender inequality in wealth as a result of skyrocketing real estate prices in recent years".
At Pandu in India's Assam state, for four decades after the quake, the river carried about 400m tonnes of suspended particles each year by mass, the annual load was more than the world's entire fleet of bulk cargo ships can carry today.One of the side effects of this migration of sediment has been a dramatic widening of the rivers.
Representation of white residents is higher at the lower ends of the BMI distribution, and there is a dramatic widening for blacks at the upper end of the BMI distribution.
This straightening of helices 4 and 5 and helices 10 and 11 resulted in the dramatic widening of the distance between the extracellular ends of these helices (see also third and fourth arrows from the left in Figures 2 and 3).
Anticipated evidence from demonstration projects, open-label PrEP studies, follow-on projects, and RCT extensions will provide a much needed dramatic widening of our knowledge base in the next several years.
One feature that was very apparent in these simulations was the dramatic widening of the extracellular ends of transmembrane helices 3/9, 4/10, 5/11, and 6/12 (as quantitatively shown in Figures 2 and 3).
This has been brought home many times in recent years, from the bond-market crash in 1994, to the turmoil in financial markets sparked by Russia's default last year, to the dramatic widening of credit spreads in America this year.
