Sentence examples for in a developmental defect from inspiring English sources

A conditional Gata3 deficiency starting from the hematopoietic stem cell stage mediated by VavCre results in a developmental defect affecting almost all ILCs (Yagi et al., 2014), consistent with another report showing that a Gata3 germline deletion causes the failure of ILC3 development (Serafini et al., 2014).

The mechanism for how RN arises in these individuals is unclear, but it has been suggested that some of these patients might have 'congenital RN', in which a developmental defect leads to abnormal formation of the UVJ and the kidney such that there is histological evidence of focal or diffuse renal hypoplasia.

These regions of the corpus callosum also were smaller in child and adolescent offspring of women with MDD who had not yet developed a mood disorder, relative to age-matched controls, suggesting that the reduction in white matter in MDD reflects a developmental defect that exists prior to illness onset (Martinez et al. 2002).

The time course of behavioral deficits, as well as the nature of the morphological defects in neuromuscular junctions, suggests that disruption of dynein function in Cra1/+ mice causes a developmental defect in synapse assembly or stabilization.

LGR5 gene knockout in mouse results in neonatal lethality due to a developmental defect in the tongue [20].

We suggest that the FGCB in unexplained infant deaths is a developmental defect in neuronal proliferation, migration, and/or cell survival in the DG.

We also found that the subepidermal nerve plexus is unaffected in Cbfb CKO mice, indicating a developmental defect in the final stage of peripheral target innervation.

Importantly, the most striking phenotype in female Rpn13−/− mice was a developmental defect in the ovaries.

We concluded the adult impairment to glucose homeostasis observed in TGPAT mice was likely to be caused by a developmental defect in endocrine pancreatic development.

However, as we added in the text: "This decrease was not due to a developmental defect in the SVZ, as we did not find any significant differences in the type C cell (DLX2+, DCX-negative) population nor a deficit in the type B cell (GFAP+, Nestin+) population in hGFAP-cre Ezh2 hGFAP-cre Ezh2

The congenital, but not hereditary, T-cell deficiency disease called DiGeorge syndrome arises from a developmental defect occurring in the fetus that results in the defective development of the thymus.