Sentence examples for in a destabilization from inspiring English sources

Incubation at physiological conditions induced ester hydrolysis resulting in a destabilization of the particles making these particles suitable for drug delivery purposes.

We found that mutation of Trp8 resulted in a destabilization of the peptide and a less rigid hydrophobic core.

Indeed, it is known that the stretching of the corona chains results in a destabilization of the spherical shape, giving rise to rod-like morphologies [ 55].

Initiation of RNA synthesis by the polymerase thus requires first an opening of the edge base pair G3 C17, which would then result in a destabilization of the whole stem.

In previous studies also a destabilization of ManII and β-1,4-GalT1 was noticed in the COG1 patient, likely explaining the observed demannosylation and galactosylation defects.

Alternatively, mutation to the smaller aliphatic amino acid side chains led to a destabilization in the active site structure which was accompanied by increases in the partition ratios associated with abortive complex formation.

· History has shown us that when new technologies have been introduced, humanity has experienced a destabilization in the balance of power.

In the Y354E mutant, the cation-π interaction is absent which in turn leads to a destabilization of the TPR2A TPR2B arrangement.

Using our gain-of-function approach, we show that an increase in miR-308 causes a destabilization of dMyc mRNA and reduced dMyc protein levels.

This leads to an increase of hyperphosphorylated Tau in the cytosol and a destabilization of the microtubule network (Cowan et al., 2010; Feuillette et al., 2010).

This points to a destabilization in the connection of the Golgi cisternae with the underlying cytoskeleton and suggests, besides a role in retrograde transport, an additional function of the COG complex (or one or more of its subunits) in tethering Golgi membranes to microtubules.