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In a continuous schedule, sensory neuropathy was dose limiting.
The recommended dose is 7.5 12 mg/kg/d in a continuous schedule and main toxicities include rash, asthenia, diarrhea, nausea and muscle cramps, as with imatinib.
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During the first three sessions animals were placed in the boxes for 30 min and the liquid reinforcer was available in the magazine on a continuous schedule.
In this Phase I open-label dose-escalation study (CBKM120X1101; NCT01283503), oral buparlisib was administered once daily, on a continuous schedule in 28-day cycles, starting at 25 mg/day.
Comparing workers with different work schedules in Spain, Amuedo-Dorantes and De la Rica (2006) find that most women are constrained in their work schedules, i.e. they would rather work a continuous schedule, and do not find evidence of a compensating wage differential for having a split work schedule.
The drug was recently registered in CML and the therapeutic dose is 400 mg twice daily on a continuous schedule.
They're subjected to a continuous schedule of exam assessments.
We chose to apply VPA on a continuous schedule.
A continuous schedule of temozolomide was developed to be given throughout the patient's radiotherapy; this was shown to be safe and active in patients with glioma.
During reinforcement blocks, points were earned on a continuous schedule (details below).
The recommended phase II dose is 150 mg orally per day on a continuous schedule.
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