Sentence examples for in a context-specific manner from inspiring English sources
We also investigated IL-6-induced signalling, which has been associated in a context-specific manner with both a deleterious proinflammatory and protective anti-inflammatory profile31.
Our results demonstrate that the Ras/Erk pathway is decoded by both dynamic filters and logic gates to shape target gene responses in a context-specific manner.
Finally, the BN provides an initial forecasting tool to model the PEC of a drug as a function of a combination of measures in a context-specific manner and possible adaptations of the model are proposed.
Fibulin-5 is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo.
Our findings identify FBLN-5 as a novel TGF-beta-inducible target gene that regulates cell growth and motility in a context-specific manner and affects protein kinase activation by TGF-beta.
In addition, the mediator kinase module behaves in a context-specific manner to either repress or activate transcription, depending on the transcription factors and/or target gene promoters (Nemet et al. 2014).
Our prediction was that, if males use such song parameters to communicate their competitive ability, then they should modify song parameters in a context-specific manner.
Indeed, several lines of evidence revealed that many Pax6 target genes are regulated in a context specific manner (Kiselev et al., 2012; Wolf et al., 2009; Xie et al., 2013).
This is a considerable challenge in view of the numerous putative functions for SMN and calpains, as well as the likelihood that calpain cleaves only a subpopulation of SMN in a context specific manner.
