Interesting areas for further study may include elucidating the role of post-translational modifications in A-Complex formation and regulation.
This cluster contains four proteins with known or presumed roles in actin cytoskeleton structure, and a complex formation between them is quite likely.
That these subunits interact to form a complex and that the putative complex interacts with Oct-1 in vitro [ 13] strongly suggest their relevance to the OCA-S activity and a complex formation in living cells.
Subsequently, a complex formation occurs in multiple series-parallel steps involving many SO2∗ and O2 per mole of NO.
The exact expression of the half bistatic angle is obtained through the solution of a four-order equation, which results in a relatively complex formation of the solution of the exact analytical spectrum.
In a ternary complex formation assay, the apparent dissociation constant (Kd,app) for dADP was greater than 100 µM (Fig. 3B); by contrast, a similar experiment in which binding of dATP was measured demonstrated a Kd,app of approximately 9.2 µM [5].
The interaction between LdUfm1 and LdUba5C217S mutant results in an irreversible complex formation and presumably resulting in reduced Ufm1 availability (Figure 1D).
2PHD2 binding to HIF1α results in an unstable complex formation and after hydroxylation of HIF1α, PHD2 is released back from the complex.
The GTP ribose 3'OH may stabilize the Glu106 residue in trans in a conformation allowing complex formation and in an orientation required for activation of the catalytic water molecule in cis.
In contrast, depletion of SNTA1 or P66shc expression using siRNAs resulted in a decrease in Sos1-Eps8-E3b1 Sos1-Eps8-E3b1 Sos1-Eps8-E3b1significomplexiformations Sos1-Grb2 complex formandon in these breast cancer cells.
