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These data indicate that L2/3 pyramidal neurons target L1 interneurons in a class-specific manner.
It was observed that a number of charged and aromatic residues are conserved in a class-specific manner on the surface of these proteins, suggesting their importance in complex formation and ligand interaction (Supplementary Fig. 18).
Initial surveying of the methylome found in Day-7 and Day-12 bovine embryos suggests a transition during development of methylation marks in repeat containing elements in a class-specific manner showing the potential of the platform to describe the ontology of the establishment of methylation marks during early embryogenesis.
Another interesting hypothesis has been proposed: the different CheWs may recognize MCPs in a class-specific manner, which produces different specific signaling pathways in a che cluster [ 54]. (3) Finally, cheD and other non- che genes – not found in the E. coli chemotaxis cluster, are present in the E. coli-like Geobacter Type 2 clusters.
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DEX acts in a gene class-specific manner in cartilage in which it promotes the expression of ECM and metabolic transcripts necessary for maintaining the chondrocyte phenotype while simultaneously downregulating cytokines and growth factors which stimulate the cartilage to bone transition.
Additionally, due to common structural features of different lipid classes, often regulated by the same enzymes in class-specific manner, there is a large degree of co-regulation to be expected in cellular, tissue, or biofluid lipid profiles.
A Wildcat is a class-specific cheer.
Basic-helix-loop-helix transcription factors are classified into two groups, that is, those ubiquitously expressed (class I), including E12/47, and those expressed in a tissue-specific manner (class II), including Olig1 (Massari and Murre, 2000).
We discovered that EZN4150 targets both p110α and Vps34 in a sequence-specific manner, thus inhibiting both class I p110α PI3K signaling and pro-survival autophagy driven by class III PI3K/Vps34 signaling, producing a potent induction of tumor cell death.
This indicates that the expansion of different classes has occurred independently in a species-specific manner in rice and Arabidopsis.
In contrast, in the model plant Arabidopsis, there are eight actin genes, which can be divided into vegetative and reproductive classes, and are expressed in a tissue-specific manner [ 52].
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