As the models were trained with continuous ln EC50 values but largely applied in a binary classification setting, we tested if training of the models as pure binary classifiers offered any advantages.
Therefore, to achieve optimized EON-controlled transgene expression from transgenic AAVs arranged in a binary vector set, the transrepressor-encoding AAV has to be administered in excess compared to the transgene-encoding counterpart or cell lines have to be used, which are particular susceptible to AAV-based transduction.
In the binary setting, such circumstances can be encountered when data are unbalanced with respect to the diagnostic groups.
In the following, we use the notation −c to denote the element other than c in the binary set C. Assume that the action profile p = (p1, p2), with p1 = (p11, p12) and p2 = (p21, p22) is an NE of the game G ( a ), and assume that for all ( k, s ) ∈ K × S, pk,s > 0, with strict inequality.
The gene set data was stored in a binary matrix with rows representing genes and columns representing gene sets.
The miR-mRNA pairs from the interactions set are reported in a binary format, as being either functional or non-functional, and we use the area under the ROC curve (AUC) measure to evaluate the sensitivity and specificity of our prediction method.
These stars were probably twin suns in a binary system.
In a RBN model, the state of each gene is a binary variable set by Boolean functions of other genes.
Next, we considered a binary data set encoding results of ChIP-on-chip experiments in S. cerevisiae.
In the functional modelling of language, form does not disappear as sometimes implied in setting a binary choice between form and function; nor need it be notional (if notional means intuitive).
