Sentence examples for imputed probabilities from inspiring English sources

Specifically, where p ij1 and p ij2 denote the imputed probabilities that the ith individual carries heterozygous and rare homozygous genotypes, respectively, at the jth variant.

In addition the dosage/copies of the B allele for each genotype was computed as p AB +2× p BB, where p AB and p BB are imputed probabilities of AB and BB genotypes, respectively.

The weighted SNP-GRSS constructed from imputed probabilities of risk alleles performed best and was highly associated with BMI (p = 4.3×10−16) accounting for 3% of the phenotypic variance.

Since the proportion of cases and controls deviates significantly from the standard 1 1, we also considered the possibility that the imputed genotype probabilities for each marker were different in both subsets.

Although there were no statistical differences in effect sizes by GRSS method, the proportion of variance in BMI accounted for increased by 0.6-0.9 0.6-0.9sing weighted scores and in the EA sample an additional 0.2% when incorporating impusinggenotype probabilities (Additional file 3: Table S3c).

In the first step we imputed a probability distribution for the genotypes of each pair of parents, conditional on the observed genotypes of all family members.

Note, in this scenario, nij may not be an integer due to imputation probabilities being reported rather than imputed genotypes.

Allele probabilities [ 18] are calculated for all SNP for all animals in the pedigree and alleles are imputed when these probabilities are >0.99.

GTOOL v0.7.0 was used to convert imputed genotyped posterior probabilities into calls.

Finally, using the updated dataset, which now includes a large number of imputed SNP, allele probabilities are re-calculated for all SNP for all animals in the pedigree.

Now suppose that each individual has an imputed genotype: the probabilities of it being imputed as TT, Tt, and tt are Q TT, Q Tt, and Q tt and the imputed allelic dosage is q T = Q TT + Q Tt/2.