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The imputed assignments provide an input to a number of proposed procedures for testing association at a microsatellite level or of a sequence of SNPs.
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Individual missing items for the SF-12® were imputed using assignment of mean score (AMS) [ 35, 36].
The imputation methods allowed for population-level comparisons with other oncology data; however, at the individual record level, our validation study showed that the imputed data assignment may vary considerably from the true value, such that analyses that rely on individual-level imputed values will have errors due to incorrect classification.
For this purpose, we developed a method of analysis where complete, phase-solved, posterior-weighted haplotype assignments are imputed for each study individual from incomplete, multi-locus, genotyping data.
Counts in each contingency table are derived from the most likely copy number assignment across the multiply imputed datasets.
Case-control counts shown are derived from the most likely copy number assignment across the ten multiply imputed qPCR and SNP datasets.
The genotypes of CC lines were imputed at MDA resolution by assembling MDA founder genotypes according to the haplotype mosaics inferred from the founder assignment algorithm described previously.
The rest was imputed rent.
Multiply imputed data.
Missing data were not imputed.
Ten imputed data sets were created.
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