Your English writing platform
Discover LudwigSuggestions(1)
Exact(10)
After SNP imputation, we included the imputed SNPs for the association study.
Individual genotypes are now available on almost 2 million measured and imputed SNPs for a subsample of TEDS.
The median genotype concordance r 2 for the 1,081,155 imputed SNPs for the European Geuvadis samples was r 2 = 0.92.
The Global BPgen consortium tested 2.5 million genotyped or imputed SNPs for association with systolic or diastolic blood pressure in 34,433 subjects of European ancestry [89] and identified eight regions with genome-wide significance.
Therefore, it is possible to devise a new customized SNP array that includes all of the selected SNPs consisting those of genotyped or imputed SNPs for the HLA-prediction model to increase the prediction accuracy.
Indeed, the HapMap imputed SNPs for the MEDIA study only cover 43.3%% of common SNPs in the 1000 Genomes ASW population at r ≥ 0.8, which partly explains the low number of genome-wide significant loci found in African Americans [ 26].
Similar(50)
To do this, we calculated the probability of being on the same chromosome as the imputed SNP for the 20 SNPs in greatest LD with the imputed SNP. Figure 2 shows that for the SNP with the highest LD, there is a probability of 0.7 of being on the same chromosome and that this drops off to 0.31 for the 20th-ranked SNP.
There is no known method for effectively filtering the poorly imputed SNPs from the well imputed SNPs on different platforms.
PLINK (v1.07) (http://pngu.mgh.harvard.edu/~purcell/plink/) [ 32] was used for GWASs of genotyped SNPs in DCCT/EDIC, PLINK (v1.90alpha) in LifeLines, R (v2.15.2; www.r-project.org/) for imputed SNPs and for the generation of plots and calculation of genomic control lambda (GenABEL; www.genabel.org/).org/
After evidence for strong linkage in this region (125906 bp to 125960 bp) on chromosome 5, we conducted fine-mapping using experimentally and imputed SNPs genotypes for an average map density of less than 1 kb.
Compared to correlation between observed and imputed genotypes, percentage of correctly imputed SNPs does not account for the (low) MAF of imputed SNPs.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com