Sentence examples for imputation scores from inspiring English sources

Therefore, we concluded that BPCAfill can produce significantly better imputation scores than simply imputing with the average score.

For rs1046099 and rs17519417 the imputation scores were 0.88 and 1 respectively, in the GRIV and in the ACS.

Iwata and Jannink (2010) determined the imputation scores of untyped markers in a low-density genotyped panel by referencing a high-density panel in barley.

For context, each of these SNPs was directly genotyped in 2 of the 7 populations, imputation was performed using very conservative metrics [ 25], and the imputation scores for these SNPs demonstrated good confidence (Additional file 5: Table S2).

Although there are only low to moderate correlations between different types of scores, it is still possible to make full use of those relationships to obtain better imputation scores.

For this analysis, the real and imputed (imputation score > 0.8) genotypes were used, and a MAF threshold of 5% for these SNPs was set.

When the imputation score (a measure for the reliability of the imputation) was below 0.8, imputation was considered unreliable and data was therefore not used.

SNPs with an imputation score > 0.8 and present originally in one or both datasets were extracted and 417,708 SNPs remained for all further analyses.

A total of 1,948,138 single nucleotide polymorphisms (SNPs) with minor allele frequency >1% and imputation score (Rsq) >0.5 were used for the analysis.

Although the imputation score for this variant was good (IMPUTE2 info score of 0.862), this distribution may reflect the fact that rs73885319 was imputed in ARIC (but genotyped in both HUFS and NHAAN).

Quality control filters were applied to the assayed genotypes to restrict the imputation to samples and SNPs with high data quality [i.e. imputation score <0.3 (indicating low imputation confidence; ∼3%), a minor allele frequency <0.01 or a Hardy Weinberg equilibrium score of P < 10−6 (∼5%)].