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Overall, 22.97% of women and 29.88% of men had either smoking or body mass index imputed by multiple imputation (data were not imputed for ethnicity all patients with missing ethnicity were treated as white/not recorded).
We performed all analyses twice including missing information as separate categories in the covariates and also by imputing missing information with multiple imputation (data not shown), showing no substantial difference in results.
After imputation, data from the eleven states were combined and analyzed.
We then extend the CMAT to probabilistic genotypes and describe application to low-coverage sequencing and imputation data.
Robustness to missing data is tackled by means of simple imputation (data replacement) schemes, such as exponential forecasts and spatial interpolation.
Using missing value imputation, data for 13,138 children were analysed.
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No imputation or data modeling was used to replace missing data.
Imputation of data will be undertaken where preintervention has been collected but postintervention data are missing.
Data processing followed the same steps as listed above for missing value imputation and data normalization.
No other imputation of data was performed.
Results were robust to the choice of imputation algorithm (data not shown).
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