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The goal, says Barsan, is to use an existing neurological trials network as a laboratory to examine this strategy for improving trials.
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(iii) To assess the effectiveness and potential of such systems in improving trial recruitment rates.
Recently created in 2010, the Patient-Centered Outcomesupportsch Institute (PCORI) supports patient-centered comparativeffectivenessss research with a focus on prioritizing high-impact studies and improving trial design methodology.
Larger randomised controlled trials are needed, particularly those focusing on improving trial methodology and reporting.
As the concept develops, interested individuals and organisations will ideally work together to develop detailed policies aimed at improving trial publication practices.
We also review regulatory guidelines for end points and trial design and recommend ways to improve trials.
The findings, published in the journal Alzheimer's & Dementia, will be used to improve trials for new dementia drugs.
Serum biomarkers predictive of disease state will improve trials for therapeutic intervention, and disease monitoring, particularly in genetically susceptible individuals.
Overall, the results of recent lupus trials challenge the rheumatology community to improve trial approaches in SLE, a patient population in need of improved therapies.
The following year, the State Legislature passed a law intended to improve trial representation for poor defendants in all criminal cases.
In the future, improved trial designs will be employed to test compounds designed specifically to treat prion diseases.
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